Apr 22, 2026
In this episode of the NCS Podcast Hot Topics series, host Richard Choi, DO, FNCS, is joined by Melissa Dang, PharmD, BCCCP, neurocritical care pharmacist at MedStar Franklin Square Medical Center, to discuss the article “Levetiracetam Dosing Optimization in Neurocritical Care Population: Neuro-ARC Study”, recently published in Neurocritical Care.
Their conversation explores
how augmented renal clearance may reduce levetiracetam exposure in
neurocritical care patients and the implications for seizure
management in clinical practice. Dr. Dang breaks down the study’s
pharmacokinetic modeling, highlights key dosing findings and
reviews the patient factors most strongly associated with increased
drug clearance. She also discusses the study’s limitations and
emphasizes the need for caution when applying its findings across
broader clinical settings.
The views expressed on the NCS Podcast are solely those of the
hosts and guests and do not necessarily reflect the opinions or
official positions of the Neurocritical Care
Society.